Isobutylamine → 4-Bromo-2-fluoro-N-(2-methylpropyl)benzamide

HRID 16106

Reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([F:11])[CH:3]=1.[CH3:12][CH:13]([CH3:16])[CH2:14][NH2:15]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:15][CH2:14][CH:13]([CH3:16])[CH3:12])=[O:8])=[C:4]([F:11])[CH:3]=1

Participants

Reactant 2

HCID 6558Isobutylamine

HCID 3026814-Bromo-2-fluorobenzoic acid

Product 1

HCID 247050334-Bromo-2-fluoro-N-(2-methylpropyl)benzamide

Procedure

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluorobenzoic acid and 2-methyl-1-propanamine.

Sources & evidence

ORD record: ord-d2ad16debc0b45e9a5dde703d8378f8c
Source dataset: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07737135B2

Linked notes

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