Ammonia → HCID 10091730, compound
Reaction equation
[O:1]1[C:5]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[OH:12])=[CH:4][CH:3]=[N:2]1.[OH:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][CH:23]=1)[C:17](OC)=O.[NH3:24]>>[O:1]1[C:5]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[O:12][CH2:8][CH2:7][CH2:6][CH:11]([CH3:10])[O:13][C:14]2[CH:23]=[CH:22][CH:21]=[C:16]3[C:15]=2[N:24]=[C:3]([NH2:2])[CH:4]=[CH:17]3)=[CH:4][CH:3]=[N:2]1Participants
4
Procedure
The title compound was prepared according to the procedure described in Example 92 substituting 2-isoxazol-5-ylphenol for methyl 3-hydroxybenzoate. 1H NMR (500 MHz, CDCl3) δ ppm 8.20 (d, 1H), 7.92 (d, 1H), 7.86 (dd, 1H), 7.34 (m, 1H), 7.23 (t, 1H), 7.16 (dd, 1H), 7.05 (d, 1H), 6.97 (m, 3H), 6.68 (d, 1H), 4.71 (m, 1H), 4.26 (m, 1H), 4.15 (m, 1H), 1.98–2.26 (m, 4H), 1.48 (d, 3H); MS (DCI/NH3) m/z 390 [M+H]+.
Sources & evidence
- ORD record
- ord-21e8e92c53ef4332af39bb08c7e8ccc3