4-Bromo-2-fluorobenzoic acid → Benzamide, 4-bromo-2-fluoro-N-methyl-

HRID 16117

Reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[C:4]([F:11])[CH:3]=1.Cl.[CH3:13][NH2:14]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:14][CH3:13])=[O:7])=[C:4]([F:11])[CH:3]=1

Participants

Reactant 2

HCID 3026814-Bromo-2-fluorobenzoic acid

HCID 6364545Methylamine hydrochloride

Product 1

HCID 24694329Benzamide, 4-bromo-2-fluoro-N-methyl-

Procedure

The sub-title compound was prepared by the method of example 18 step a) using 4-bromo-2-fluorobenzoic acid and methylamine hydrochloride.

Sources & evidence

ORD record: ord-dc25e8728ed9419292ce3c6842ce86a5
Source dataset: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07737135B2

Linked notes

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