Ammonia → 4-(3-Aminomethylphenyl)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]azetidin-2-one
Reaction equation
[H][H].[F:3][C:4]1[CH:9]=[CH:8][C:7]([CH:10]([OH:45])[CH2:11][CH2:12][CH:13]([C:31](N2C(C3C=CC=CC=3)COC2=O)=[O:32])[CH:14]([C:23]2[CH:30]=[CH:29][C:26](C#N)=[CH:25][CH:24]=2)[NH:15][C:16]2[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=2)=[CH:6][CH:5]=1.[NH3:46].[CH2:47](O)C>[Ni]>[NH2:46][CH2:47][C:25]1[CH:24]=[C:23]([CH:14]2[N:15]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)[C:31](=[O:32])[CH:13]2[CH2:12][CH2:11][CH:10]([C:7]2[CH:6]=[CH:5][C:4]([F:3])=[CH:9][CH:8]=2)[OH:45])[CH:30]=[CH:29][CH:26]=1Participants
6
