Chlorosulfamic acid → 2-(4-Chlorophenoxy)-2-methylpropanol sulfamate

Reaction equation

[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[Cl:6][C:7]1[CH:18]=[CH:17][C:10]([O:11][C:12]([CH3:16])([CH3:15])[CH2:13][OH:14])=[CH:9][CH:8]=1>>[S:1]([O:14][CH2:13][C:12]([O:11][C:10]1[CH:17]=[CH:18][C:7]([Cl:6])=[CH:8][CH:9]=1)([CH3:15])[CH3:16])(=[O:4])(=[O:3])[NH2:2]

Participants

Reactant 2

HCID 24499Chlorosulfamic acid

HCID 191086602-(4-Chlorophenoxy)-2-methylpropan-1-ol

Product 1

HCID 197334572-(4-Chlorophenoxy)-2-methylpropanol sulfamateYield 58%

Procedure

The title compound was prepared by procedures of Example 33 from sulfamoyl chloride and 2-(4-chlorophenoxy)-2-methylpropanol to give white solid, mp 76°-79° C., in 58% yield.

Workup

customto give white solid, mp 76°-79° C.

Sources & evidence

ORD record: ord-238918120b8b48aa91db574466eb15d8
Source dataset: uspto-grants-1993_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05194446

Reaction notes

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