Benzene, (3-bromopropoxy)- → 2-Cyano-1-(3-phenoxypropyl)piperidine

HRID 1614610

Reaction equation

HRID 1614610 reaction equation
[O:1]([CH2:8][CH2:9][CH2:10]Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:12]([CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][NH:15]1)#[N:13]>>[C:12]([CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][N:15]1[CH2:10][CH2:9][CH2:8][O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)#[N:13]

Participants

3

Reactant 2

HCID 68522Benzene, (3-bromopropoxy)-HCID 1551382-Cyanopiperidine

Product 1

HCID 197719582-Cyano-1-(3-phenoxypropyl)piperidine

Procedure

Following the procedure of Preparation 9, the title compound is prepared from 3-phenoxypropyl bromide and 2-cyanopiperidine [Chem. Ber. 92, 1608-1613 (1959), Helv. Chim. Acta 46(4), 1190-1206 (1963)].

Workup

  1. customthe procedure of Preparation 9

Sources & evidence

ORD record
ord-0c91897047234f5a96d0cf9506b548a3
Source dataset
uspto-grants-1993_03
Patent number
US05198449

Linked notes

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