2-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acid → 2-Pyridin-4-yl-thiazole-4-carboxylic acid [2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amide

HRID 161522

Reaction equation

HRID 161522 reaction equation
[CH3:1][c:2]1[c:3]([NH2:19])[cH:4][cH:5][c:6]([N:8]2[CH2:9][CH:10]([N:13]3[CH:14]([CH3:18])[CH2:15][CH2:16][CH2:17]3)[CH2:11][CH2:12]2)[cH:7]1.[n:20]1[cH:21][cH:22][c:23](-[c:26]2[s:27][cH:28][c:29]([C:31](=[O:32])[OH:33])[n:30]2)[cH:24][cH:25]1>>[CH3:1][c:2]1[c:3]([NH:19][C:31]([c:29]2[cH:28][s:27][c:26](-[c:23]3[cH:22][cH:21][n:20][cH:25][cH:24]3)[n:30]2)=[O:32])[cH:4][cH:5][c:6]([N:8]2[CH2:9][CH:10]([N:13]3[CH:14]([CH3:18])[CH2:15][CH2:16][CH2:17]3)[CH2:11][CH2:12]2)[cH:7]1

Participants

3

Reactant 2

HCID 7160912-(Pyridin-4-yl)-1,3-thiazole-4-carboxylic acidHCID 594018302-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamine

Product 1

HCID 594018012-Pyridin-4-yl-thiazole-4-carboxylic acid [2-methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-amide

Sources & evidence

ORD record
ord-ece37a5622d1431495ee707fbd95752b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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