2-(6-Iodo-benzofuran-3-yl)-ethylamine → 2-(6-Iodo-benzofuran-3-yl)-2-methyl-propylamine
Reaction equation
IC1C=CC2C(CCN)=COC=2C=1.[I:14][C:15]1[CH:28]=[CH:27][C:18]2[C:19]([C:22]([CH3:26])([CH3:25])[C:23]#[N:24])=[CH:20][O:21][C:17]=2[CH:16]=1>>[I:14][C:15]1[CH:28]=[CH:27][C:18]2[C:19]([C:22]([CH3:26])([CH3:25])[CH2:23][NH2:24])=[CH:20][O:21][C:17]=2[CH:16]=1Participants
3
Procedure
Synthesized as described for 2-(6-iodo-1-benzofuran-3-yl)ethanamine using 2-(6-iodo-benzofuran-3-yl)-2-methyl-propionitrile as the starting material.
Workup
- customSynthesized
Sources & evidence
- ORD record
- ord-932a2cd3f9754c69a3145cd2ae4ce0d1
- Source dataset
- uspto-grants-2014_07
- Patent number
- US08765779B2
Reaction notes
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