Hydrazine → 2,4-Dimethylbenzohydrazide

HRID 1625576

Reaction equation

HRID 1625576 reaction equation
[CH3:1][C:2]1[CH:11]=[C:10]([CH3:12])[CH:9]=[CH:8][C:3]=1[C:4](OC)=[O:5].[NH2:13][NH2:14]>CO>[CH3:1][C:2]1[CH:11]=[C:10]([CH3:12])[CH:9]=[CH:8][C:3]=1[C:4]([NH:13][NH2:14])=[O:5]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 32031Methyl 2,4-dimethylbenzoate

Product 1

HCID 48461732,4-Dimethylbenzohydrazide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of methyl 2,4-dimethylbenzoate (2 g, 12.2 mmol) in MeOH (10 mL) was added anhydrous hydrazine (1.95 mL, 61 mmol) and the mixture was heated under reflux for 40 hours. Then the mixture was evaporated and dried under vacuum to give 2,4-dimethylbenzohydrazide as a white solid (2 g, 100%; MS (M+H, 165).

Workup

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 40 hours
  3. customThen the mixture was evaporated
  4. customdried under vacuum

Sources & evidence

ORD record
ord-0c7a3d9d10ba4e2b964212cfbbb97f70
Source dataset
uspto-grants-2014_07
Patent number
US08784782B2

Linked notes

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