Pyridine → N-[5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-4-[(dimethylamino)methyl]benzamide

HRID 162865

Reaction equation

HRID 162865 reaction equation
[CH3:25][N:26]([CH3:27])[CH2:28][c:29]1[cH:30][cH:31][c:32]([C:33](=[O:34])[Cl:35])[cH:36][cH:37]1.[CH:1]1([NH:4][c:5]2[cH:6][c:7]([C:15]([F:16])([F:17])[F:18])[cH:8][c:9]3[n:10]2[n:11][c:12]([NH2:14])[n:13]3)[CH2:2][CH2:3]1.[Cl:38][CH2:39][Cl:40].[cH:19]1[cH:20][cH:21][n:22][cH:23][cH:24]1>>[CH:1]1([NH:4][c:5]2[cH:6][c:7]([C:15]([F:16])([F:17])[F:18])[cH:8][c:9]3[n:10]2[n:11][c:12]([NH:14][C:33]([c:32]2[cH:31][cH:30][c:29]([CH2:28][N:26]([CH3:25])[CH3:27])[cH:37][cH:36]2)=[O:34])[n:13]3)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 137489654-(N,N-dimethylaminomethyl) benzoyl chlorideHCID 59437445N5-cyclopropyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridine-2,5-diamine

Product 1

HCID 59437472N-[5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-4-[(dimethylamino)methyl]benzamide

Sources & evidence

ORD record
ord-cf1186cb421e4069a019fc31cb1582ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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