Pyridine → ethyl 7-({[2-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-indole-2-carboxylate

HRID 163252

Reaction equation

HRID 163252 reaction equation
[F:16][C:17]([c:18]1[c:19]([S:24](=[O:25])(=[O:26])[Cl:27])[cH:20][cH:21][cH:22][cH:23]1)([F:28])[F:29].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[nH:9][c:10]12.[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][c:6]2[cH:7][c:8]([C:11](=[O:12])[O:13][CH2:14][CH3:15])[nH:9][c:10]12)[S:24]([c:19]1[c:18]([C:17]([F:16])([F:28])[F:29])[cH:23][cH:22][cH:21][cH:20]1)(=[O:25])=[O:26]

Participants

4

Reactant 3

HCID 1049PyridineHCID 1366162-Trifluoromethylbenzenesulphonyl chlorideHCID 111381941H-Indole-2-carboxylic acid, 7-amino-, ethyl ester

Product 1

HCID 57476178ethyl 7-({[2-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-indole-2-carboxylate

Sources & evidence

ORD record
ord-8e604beaca52450388880d9608f9220f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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