Acetate → 4-(5-(1-(Tert-butyldimethylsilyloxy)-2-methylpropan-2-yl)-2-fluoropyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

HRID 163593

Reaction equation

HRID 163593 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][C:8]([CH3:9])([CH3:10])[c:11]1[cH:12][c:13]([B:18]([OH:19])[OH:20])[c:14]([F:17])[n:15][cH:16]1)([CH3:21])[CH3:22].[CH3:33][C:34](=[O:35])[O-:36].[Cl:23][c:24]1[n:25][c:26]([NH2:31])[n:27][c:28]([CH3:30])[n:29]1.[K+:32].[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[OH2:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][C:8]([CH3:9])([CH3:10])[c:11]1[cH:12][c:13](-[c:24]2[n:25][c:26]([NH2:31])[n:27][c:28]([CH3:30])[n:29]2)[c:14]([F:17])[n:15][cH:16]1)([CH3:21])[CH3:22]

Participants

7

Reactant 6

HCID 175AcetateHCID 813Potassium CationHCID 962WaterHCID 305914-Chloro-6-methyl-1,3,5-triazin-2-amineHCID 312751,4-DioxaneHCID 665999945-(1-(Tert-butyldimethylsilyloxy)-2-methylpropan-2-yl)-2-fluoropyridin-3-ylboronic acid

Product 1

HCID 666114554-(5-(1-(Tert-butyldimethylsilyloxy)-2-methylpropan-2-yl)-2-fluoropyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

Sources & evidence

ORD record
ord-69bd3a873e0849a0ae469ce9b8919da7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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