2-t-Butyl-5-cyano-1-nitrobenzene → Benzonitrile, 3-amino-4-(1,1-dimethylethyl)-
Reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[N:12])=[CH:7][C:6]=1[N+:13]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>CCCCCC.C(OCC)(=O)C>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]#[N:12])=[CH:7][C:6]=1[NH2:13])([CH3:4])([CH3:2])[CH3:3]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
2-t-Butyl-5-cyano-l-nitrobenzene [prepared as described in step (i) above] was reduced in a similar manner to that described in Preparation 5 to give the title compound as crystals, melting at 94.5-95° C. (from hexane-ethyl acetate).
Workup
- customdescribed in Preparation 5
Sources & evidence
- ORD record
- ord-3974dfabb626470288ce3ca007f44db7
- Source dataset
- uspto-grants-2000_03
- Patent number
- US06040339
Reaction notes
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