4-Methylpyridine-2-carbaldehyde → 4-Ethylpyridine-2-carbaldehyde

HRID 1637741

Reaction equation

HRID 1637741 reaction equation
CC1C=CN=C(C=O)C=1.[CH2:10]([C:12]1[CH:17]=[CH:16][N:15]=[C:14]([CH2:18][OH:19])[CH:13]=1)[CH3:11]>>[CH2:10]([C:12]1[CH:17]=[CH:16][N:15]=[C:14]([CH:18]=[O:19])[CH:13]=1)[CH3:11]

Participants

3

Reactant 2

HCID 100118944-Methylpyridine-2-carbaldehydeHCID 123963882-Pyridinemethanol, 4-ethyl-

Product 1

HCID 187996004-Ethylpyridine-2-carbaldehydeYield 84.2%

Procedure

In a manner similar to that described for the preparation of 4-methyl-2-pyridine-carboxaldehyde, 4-ethyl-2-hydroxymethylpyridine (1.60 g, 11.68 mmol) yielded 1.33 g (84%) of 4-ethyl-2-pyridinecarboxaldehyde.

Sources & evidence

ORD record
ord-bbb14e86372c42bcb8683865535968d0
Source dataset
uspto-grants-2000_03
Patent number
US06043248

Linked notes

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