1-Octanol → HCID 15696565, compound

Reaction equation

[OH:1][CH:2]1[NH:6][C:5](=[O:7])[CH2:4][CH2:3]1.[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>>[CH2:8]([O:1][CH:2]1[NH:6][C:5](=[O:7])[CH2:4][CH2:3]1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

Reactant 2

HCID 9571-Octanol

HCID 1941485-Hydroxy-2-pyrrolidone

Product 1

HCID 15696565HCID 15696565, compound

Procedure

7.5 g of 5-hydroxy-pyrrolidin-2-one, 10 cm3 of n-octanol and 4 g of Amberlite IR 120H are heated to 60° C. for 4 hours. After filtering, the n-octanol is eliminated by distilling under reduced pressure. 5.5 g of the expected product is obtained, m.p. 36°-38° C., crystallized from hexane.

Workup

filtrationAfter filtering
distillationby distilling under reduced pressure

Sources & evidence

ORD record: ord-1f5cd7c854d64e72960378e2514498cf
Source dataset: uspto-grants-1989_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04882350

Reaction notes

Loading…