1,1,3,3-Tetramethyldisilazane, 97% → HCID 59227480, compound

Reaction equation

[C:1]1([C:7]#[C:8][CH2:9][OH:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1.[CH3:11][SiH:12]([CH3:17])N[SiH](C)C>>[C:1]1([C:7]#[C:8][CH2:9][O:10][SiH:12]([CH3:17])[CH3:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1

Participants

Reactant 2

HCID 851961,1,3,3-Tetramethyldisilazane, 97%

HCID 127701823-(Cyclohex-1-en-1-yl)prop-2-yn-1-ol

Product 1

HCID 59227480HCID 59227480, compoundYield 176%

Procedure

3-Cyclohexenylprop-2-yn-1-ol (2.509 g, 26.10 mmol) and 1,1,3,3-tetramethyldisilazane (1.527 g, 11.45 mmol) were used according to the method mentioned above to produce the title compound as a brown clear liquid (3.916 g, 20.15 mmol, 77.2%). The crude reaction mixture was analyzed by 1H NMR to confirm the product formation and used in KOtBu catalyzed transhydrosilylation reaction.

Sources & evidence

ORD record: ord-dc702f953bd54bcdb9d2ccfc24939a18
Source dataset: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08110695B2

Reaction notes

Loading…