(1,3-Dioxan-2-yl)methanol → (2-Methyl-1,3-dioxan-2-yl)methanol

HRID 1645587Notes

Reaction equation

HRID 1645587 reaction equation
[O:1]1[CH2:6][CH2:5][CH2:4][O:3][CH:2]1[CH2:7][OH:8].[CH2:9](OCC(=O)C)C1C=CC=CC=1>>[CH3:9][C:2]1([CH2:7][OH:8])[O:3][CH2:4][CH2:5][CH2:6][O:1]1

Participants

3

Reactant 2

HCID 142350(1,3-Dioxan-2-yl)methanolHCID 36912841-(Benzyloxy)propan-2-one

Product 1

HCID 59792415(2-Methyl-1,3-dioxan-2-yl)methanolYield 37%

Procedure

The same procedure as in the steps (32a) and (32b) of Example 32 was repeated using 1-benzyloxy-2-propanone to obtain the title compound (1.51 g, total yield: 37%) as a light yellow oil.

Sources & evidence

ORD record
ord-5a6cad0e590046aa9e7b1bd0f06386b5
Source dataset
uspto-grants-2012_02
Patent number
US08124780B2

Reaction notes

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