N-Phenylglycine → HCID 19100958, compound
Reaction equation
[CH2:1]([N:4]([CH2:10][CH:11]=O)[C:5](=[O:9])[O:6][CH2:7][CH3:8])[CH:2]=[CH2:3].[C:13]1([NH:19][CH2:20]C(O)=O)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C1(C)C=CC=CC=1>[C:13]1([N:19]2[CH2:20][CH2:3][CH:2]3[CH:11]2[CH2:10][N:4]([C:5]([O:6][CH2:7][CH3:8])=[O:9])[CH2:1]3)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
8.6 g (50 mmol) of ethyl N-allyl-N-(2-oxoethyl)-carbamate and 7.6 (50 mmol) of phenylglycine are heated under reflux overnight in 200 ml of toluene. The mixture is decanted from resinous material and concentrated, and the residue is distilled.
Workup
- customThe mixture is decanted from resinous material
- concentrationconcentrated
- distillationthe residue is distilled
Sources & evidence
- ORD record
- ord-88928769560a44cdb788de3a25928e24
- Source dataset
- uspto-grants-1993_01
- Patent number
- US05177210
Reaction notes
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