N-((1,1-dimethylethoxy)carbonyl)-beta-alanine → HCID 19926258, compound

Reaction equation

[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][C:11]([OH:13])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:14]([O:21][C:22](=[O:32])[CH2:23][CH:24]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[NH2:25])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([O:21][C:22](=[O:32])[CH2:23][CH:24]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[NH:25][C:11](=[O:13])[CH2:10][CH2:9][NH:8][C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 76809N-((1,1-dimethylethoxy)carbonyl)-beta-alanine

HCID 21459741HCID 21459741, compound

Product 1

HCID 19926258HCID 19926258, compound

Procedure

N-(t-butoxycarbonyl)-β-alanine was reacted with DL-3-phenyl-β-alanine benzyl ester to give DL-N-[N-(t-butoxycarbonyl)-β-alanyl]-3-phenyl-β-alanine benzyl ester, m.p. 124.5°-126° C.

Sources & evidence

ORD record: ord-b02496a6daec4626818a43a1abfcc538
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05430024

Reaction notes

Loading…