3-Chloro-N,N-dimethyl-1-propanamine → HCID 10131916, compound

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[CH2:16][S:15][C:14](=[O:17])[NH:13][N:12]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].Cl[CH2:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23]>>[CH3:23][N:22]([CH3:24])[CH2:21][CH2:20][CH2:19][N:13]1[N:12]=[C:11]([C:5]2[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=2)[CH2:16][S:15][C:14]1=[O:17]

Participants

Reactant 2

HCID 669603-Chloro-N,N-dimethyl-1-propanamine

HCID 133658505-(3,4-Dimethoxyphenyl)-3,6-dihydro-2H-1,3,4-thiadiazin-2-one

Product 1

HCID 10131916HCID 10131916, compound

Procedure

In analogy to Example 1, by reacting 5-(3,4-dimethoxyphenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one with 3-chloropropyldimethylamine, 3-dimethylaminopropyl-5(3,4-dimethoxyphenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one is obtained; m.p. 195°.

Sources & evidence

ORD record: ord-9e847dbdac9e41569f5a54f35e6b1e55
Source dataset: uspto-grants-1995_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05434149

Reaction notes

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