1-(2-Aminothiazol-4-yl)-1-propencarboxylic acid ethyl ester → 2-(2-Aminothiazol-4-yl)-2-butenoic acid

HRID 1649414

Reaction equation

HRID 1649414 reaction equation
C([O:3][C:4]([C:6]([C:9]1[N:10]=[C:11]([NH2:14])[S:12][CH:13]=1)=[CH:7][CH3:8])=[O:5])C>CO.[OH-].[Na+]>[NH2:14][C:11]1[S:12][CH:13]=[C:9]([C:6]([C:4]([OH:5])=[O:3])=[CH:7][CH3:8])[N:10]=1

Participants

4

Reactant 1

HCID 544043711-(2-Aminothiazol-4-yl)-1-propencarboxylic acid ethyl ester

Product 1

HCID 536703542-(2-Aminothiazol-4-yl)-2-butenoic acid

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

The product of example 82 was dissolved in a mixture of 20 ml methanol and 5 ml 2 n NaOH.

Sources & evidence

ORD record
ord-0818b089eb844f4d9e2248943ba0dc98
Source dataset
uspto-grants-1983_11
Patent number
US04416880

Linked notes

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