Methanethiol → HCID 14698107, compound
Reaction equation
[CH3:1][SH:2].F[C:4]1[CH:18]=[CH:17][C:7]([C:8]([C:10]2[S:14][C:13](=[O:15])[NH:12][C:11]=2[CH3:16])=[O:9])=[CH:6][CH:5]=1>C(O)C>[CH3:16][C:11]1[NH:12][C:13](=[O:15])[S:14][C:10]=1[C:8](=[O:9])[C:7]1[CH:17]=[CH:18][C:4]([S:2][CH3:1])=[CH:5][CH:6]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Gaseous methylmercaptan is added to a solution of 5(4-fluorobenzoyl)-4-methyl-2(3H)-thiazolone (4.7 g) in ethanol (200 ml) to saturation. The mixture is heated at 120° C. in a sealed stainless steel container for 16 hours. After cooling to ambient temperature, the mixture is evaporated to dryness. The residue is recrystallized twice from ethanol to give the title compound.
Workup
- customthe mixture is evaporated to dryness
- customThe residue is recrystallized twice from ethanol
Sources & evidence
- ORD record
- ord-0e04c0338bd647e384822d6c14c11336
- Source dataset
- uspto-grants-1990_05
- Patent number
- US04927939
Reaction notes
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