1-Chloro-2,3-dimethylbenzene → 2-(2-methylphenylmethylthio)pyridine N-oxide

HRID 1657338Notes

Reaction equation

HRID 1657338 reaction equation
Cl[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[CH3:9].[Na].[SH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N+:13]=1[O-:18]>>[CH3:8][C:4]1[CH:5]=[CH:6][CH:7]=[CH:2][C:3]=1[CH2:9][S:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][N+:13]=1[O-:18]

Participants

3

Reactant 2

HCID 328841-Chloro-2,3-dimethylbenzeneHCID 178507102HCID 178507102, compound

Product 1

HCID 456923522-(2-methylphenylmethylthio)pyridine N-oxideYield 85%

Procedure

The intermediate 2-(2-methylphenylmethylthio)-pyridine N-oxide is prepared by the procedure described in Example 2 from α -chloro o-xylene and 2-mercaptopyridine N-oxide sodium salt. Melting point 134° - 136°C. Yield 85% theory. Structure confirmed by IR and NMR.

Sources & evidence

ORD record
ord-d8a57e74253b42718067e7320b4de9cb
Source dataset
uspto-grants-1976_06
Patent number
US03960542

Reaction notes

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