1-(Pyridin-3-yl)butan-2-one → 1-(Dimethylamino)-2-pyridin-4-ylpent-1-en-3-one

Reaction equation

[CH2:1]([C:3]([C:5](C1C=NC=CC=1)=[CH:6][N:7]([CH3:9])[CH3:8])=[O:4])[CH3:2].C(C(C[C:21]1[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=1)=O)C>>[CH2:1]([C:3]([C:5]([C:26]1[CH:21]=[CH:22][N:23]=[CH:24][CH:25]=1)=[CH:6][N:7]([CH3:9])[CH3:8])=[O:4])[CH3:2]

Participants

Reactant 2

HCID 2384211-(Pyridin-3-yl)butan-2-one

HCID 54281533HCID 54281533, compound

Product 1

HCID 543010641-(Dimethylamino)-2-pyridin-4-ylpent-1-en-3-one

Procedure

A-11. 1-(3-Pyridinyl)-2-(dimethylamino)ethenyl ethyl ketone using (3-pyridinyl)methyl ethyl ketone.

Sources & evidence

ORD record: ord-380d622923ba402d94728d61963e641d
Source dataset: uspto-grants-1981_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04305948

Reaction notes

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