HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Propan-2-yl)-1,3-dihydro-2H-benzimidazol-2-one → Methyl 2-ethyl-2-{[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]methyl}butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Propan-2-yl)-1,3-dihydro-2H-benzimidazol-2-one | HCID 1653580 | — |
| Reactant | Methyl 2-[(4-{[(tert-butoxycarbonyl)amino]methyl}piperidin-1-yl)methyl]-2-ethylbutanoate | HCID 67232103 | — |
| Product | Methyl 2-ethyl-2-{[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]methyl}butanoate | HCID 68585368 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Step 2 of Example 8 from 1-isopropyl-1,3-dihydro-2H-benzimidazol-2-one and Methyl 2-[(4-{[(tert-butoxycarbonyl)amino]methyl}piperidin-1-yl)methyl]-2-ethylbutanoate (step 1 of Example 13).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07737163B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-0fb8e1043ae94a52b72a56411923d592 |
| Source note | uspto-grants-2010_06 |