5-Amino-2-chlorobenzoic acid → 2-Chloro-5-(Cyclohexanecarboxamido)Benzoic Acid

Participants

Reaction Steps

A solution of 5-amino-2-chlorobenzoic acid (0.34 g, 2.0 mmol) in THF (10 mL) was charged with cyclohexanecarbonyl chloride (0.27 mL, 1.7 mmol). The reaction was stirred for 16 h and then concentrated in vacuo. The residue was suspended in DCM and filtered to afford the title compounds as a white solid (0.47 g, 97%).

Provenance & Evidence