Nitric Acid → 3-Bromo-4-hydroxy-5-nitrobenzaldehyde

HRID 1663361

Reaction equation

HRID 1663361 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[CH:5]=[O:6].[N+:11]([O-])([OH:13])=[O:12]>C(O)(=O)C>[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=[O:6]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 763083-Bromo-4-hydroxybenzaldehyde

Product 1

HCID 14943783-Bromo-4-hydroxy-5-nitrobenzaldehyde

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

3-Bromo-4-hydroxybenzaldehyde (250 mg) was dissolved in 5 ml of acetic acid. Nitric acid (52 μl) was added and the mixture was stirred for 3 h during which a solid formed. The solid was filtered off, washed with water and dried in vacuo.

Workup

  1. customformed
  2. filtrationThe solid was filtered off
  3. washwashed with water
  4. customdried in vacuo

Sources & evidence

ORD record
ord-1f5b60dd7fee4c75b87a95ec00faca54
Source dataset
uspto-grants-2011_10
Patent number
US08034945B2

Linked notes

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