Ethanol → HCID 178481214, compound

HRID 1668273

Reaction equation

HRID 1668273 reaction equation
[C:1]1([S:7]([C:10]2[CH:15]=[CH:14][C:13]([N:16]3[C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=4[N:18]=[CH:17]3)=[CH:12][CH:11]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:25][B-:26]([F:29])([F:28])[F:27].[CH3:30][O+](C)C.C(O)C>ClCCl>[F:25][B-:26]([F:29])([F:28])[F:27].[C:1]1([S:7]([C:10]2[CH:11]=[CH:12][C:13]([N+:16]3[C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=4[N:18]([CH3:30])[CH:17]=3)=[CH:14][CH:15]=2)(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 2735153Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1)HCID 668793591-(4'-Phenylsulfonylphenyl)benzimidazole

Product 1

HCID 178481214HCID 178481214, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 1-(4′-phenylsulfonylphenyl)benzimidazole (6.7 g, 20 mmol) in dichloromethane (100 ml) is admixed at −10° C. with trimethyloxonium tetrafluoroborate (3.3 g, 22 mmol) and stirred under argon for 16 h. After adding ethanol, the precipitate which forms is filtered off and washed with cold petroleum ether. Yield: 80%.

Workup

  1. filtrationthe precipitate which forms is filtered off
  2. washwashed with cold petroleum ether

Sources & evidence

ORD record
ord-f73855ed2b2f431fbfae61338204e495
Source dataset
uspto-grants-2011_08
Patent number
US07989091B2

Linked notes

Loading…