3-Methylpyridine-2-carboximidamide → HCID 86633453, compound

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[N:3]=1.[CH3:20]C1C(C(N)=N)=NC=CC=1>>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)[N:5]=[C:4]([C:14]2[C:19]([CH3:20])=[CH:18][CH:17]=[CH:16][N:15]=2)[N:3]=1

Participants

Reactant 2

HCID 146855903-Methylpyridine-2-carboximidamide2×

HCID 283091114-Chloro-2-(pyridin-2-yl)-6-(pyridin-3-yl)pyrimidine

Product 1

HCID 86633453HCID 86633453, compound

Procedure

This compound is prepared analogously to Intermediate A by replacing pyridine-2-carboxamide (step 1) with 3-methyl-pyridine-2-carboxamidine (Intermediate C)

Sources & evidence

ORD record: ord-5ede38afd2c14d4f8b68bdbd61bf4588
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07989458B2

Reaction notes

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