Sodium Hydroxide → 4-Azidobutanoic Acid
Reaction equation
[N:1]([CH2:4][CH2:5][CH2:6][C:7]([O:9]C)=[O:8])=[N+:2]=[N-:3].[OH-].[Na+]>CO>[N:1]([CH2:4][CH2:5][CH2:6][C:7]([OH:9])=[O:8])=[N+:2]=[N-:3]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Methyl 4-azidobutanoate was suspended in 1N NaOH (1.2 eq) and the minimum of MeOH was added to make the reaction mixture homogenous. After 1 h at RT temperature, MeOH was removed in vacuo. The aqueous solution
Workup
- customAfter 1 h at RT temperature, MeOH was removed in vacuo
Sources & evidence
- ORD record
- ord-addf8ec2b522498fb66858206aa8654e
- Source dataset
- uspto-grants-2011_08
- Patent number
- US07989438B2
Reaction notes
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