Cyclohexanone, 4,4-dimethyl- → HCID 67344581, compound

Reaction equation

CC1(C)CCC(=O)CC1.C([N:20]1[CH2:24][CH2:23][C@H:22]([N:25]([CH:31]2[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]2)[CH2:26][C:27]([O:29][CH3:30])=[O:28])[CH2:21]1)(OCC1C=CC=CC=1)=O>>[NH:20]1[CH2:24][CH2:23][C@H:22]([N:25]([CH:31]2[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]2)[CH2:26][C:27]([O:29][CH3:30])=[O:28])[CH2:21]1

Participants

Reactant 2

HCID 138166Cyclohexanone, 4,4-dimethyl-

HCID 67379348methyl 2-[(3S)-1-Cbz-3-pyrolidinyl(cyclohexyl)amino]acetate2×

Product 1

HCID 67344581HCID 67344581, compound

Procedure

The title compound was prepared following the procedure described in Step B of Intermediate 3 using the product of Step A, methyl 2-[(3S)-1-Cbz-pyrrolidin-3-yl (cyclohexyl) amino]acetate.

Sources & evidence

ORD record: ord-8ade04e8c68b41adbc42c6da12056aff
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07989634B2

Reaction notes

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