(S)-1-Cbz-3-Aminopyrrolidine → HCID 67344292, compound

Reaction equation

C(N1CC[C@H](N)C1)(OCC1C=CC=CC=1)=O.C([N:24]1[CH2:29][CH2:28][CH:27]([N:30]([CH:37]2[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]2)[C:31](=[O:36])[NH:32][CH:33]([CH3:35])[CH3:34])[CH2:26][CH2:25]1)(OC(C)(C)C)=O>>[CH:37]1([N:30]([C:31](=[O:36])[NH:32][CH:33]([CH3:34])[CH3:35])[CH:27]2[CH2:28][CH2:29][NH:24][CH2:25][CH2:26]2)[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38]1

Participants

Reactant 2

HCID 1519355(S)-1-Cbz-3-Aminopyrrolidine

HCID 67346737HCID 67346737, compound

Product 1

HCID 67344292HCID 67344292, compound

Procedure

The title compound was prepared following the procedure described in Step B of Intermediate 1 using 1-BOC-4-[cyclohexyl(N-isopropylcarbamoyl)amino]piperidine.

Sources & evidence

ORD record: ord-ab95d43ded94414a977719a15cd13d18
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07989634B2

Reaction notes

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