1-Bromo-3-methylbutane → 12-Methyltridecan-1-ol

Reaction equation

Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11].[CH3:12][CH:13]([CH3:17])[CH2:14][CH2:15]Br>>[CH3:12][CH:13]([CH3:17])[CH2:14][CH2:15][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11]

Participants

Reactant 2

HCID 78911-Bromo-3-methylbutane

HCID 1087001-Nonanol, 9-bromo-

Product 1

HCID 1087853312-Methyltridecan-1-olYield 51%

Procedure

12-methyltridecan-1-ol was prepared from 9-bromononan-1-ol and 3-methylbutylbromide in 51% yield. The 1H NMR and MS-ESI data matched those reported by Yuasa et al. (Yuasa and Tsuruta (2004) Flavour and Fragrance Journal 19:199-204).

Sources & evidence

ORD record: ord-f0c13cb6cdaf40a1895ab019d1fc54a1
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07994143B2

Reaction notes

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