HCID 178447907, compound → HCID 178447906, compound

HRID 1671545Notes

Reaction equation

HRID 1671545 reaction equation
[N+:1]([C:4]1[CH:71]=[CH:70][C:7]([CH2:8][C:9]([CH2:60][C:61]2[CH:66]=[CH:65][C:64]([N+:67]([O-])=O)=[CH:63][CH:62]=2)([CH2:36][C:37](=[O:59])[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][O:43][C:44]2[CH:49]=[CH:48][C:47]([C@H:50]3[CH2:55][CH2:54][C@H:53]([CH2:56][CH2:57][CH3:58])[CH2:52][CH2:51]3)=[CH:46][CH:45]=2)[C:10]([C:13](=[O:35])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][O:19][C:20]2[CH:25]=[CH:24][C:23]([C@H:26]3[CH2:31][CH2:30][C@H:29]([CH2:32][CH2:33][CH3:34])[CH2:28][CH2:27]3)=[CH:22][CH:21]=2)([OH:12])[OH:11])=[CH:6][CH:5]=1)([O-])=O>[Zn]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH2:8][C:9]([CH2:60][C:61]2[CH:66]=[CH:65][C:64]([NH2:67])=[CH:63][CH:62]=2)([CH2:36][C:37](=[O:59])[CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][O:43][C:44]2[CH:45]=[CH:46][C:47]([C@H:50]3[CH2:51][CH2:52][C@H:53]([CH2:56][CH2:57][CH3:58])[CH2:54][CH2:55]3)=[CH:48][CH:49]=2)[C:10]([C:13](=[O:35])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][O:19][C:20]2[CH:25]=[CH:24][C:23]([C@H:26]3[CH2:27][CH2:28][C@H:29]([CH2:32][CH2:33][CH3:34])[CH2:30][CH2:31]3)=[CH:22][CH:21]=2)([OH:11])[OH:12])=[CH:70][CH:71]=1

Participants

3

Reactant 1

HCID 178447907HCID 178447907, compound

Product 1

HCID 178447906HCID 178447906, compound

Reagents, catalysts & solvents 1

HCID 23994ZincCatalyst

Procedure

Preparation can be carried out analogously to Synthetic Example 1 using 0.975 g (1.00 mmol) 2,2-bis(4-nitrobenzyl)-1,3-di{6-[4-(trans-4-propylcyclohexyl) phenoxy]hexanoyl}propanediol, 1.62 g (6.00 mmol) Ferric chloride hexahydrate and 0.65 g (10.00 mmol) Zinc powder yield 2,2-bis(4 -aminobenzyl)-1,3-di{6-[4-(trans-4-propylcyclohexyl)phenoxy]hexanoyl}propanediol.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-74343d710a95492c9900e96c96cc42f0
Source dataset
uspto-grants-2011_08
Patent number
US07994273B2

Reaction notes

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