Methacrylic Acid → 2-Methyl-4-oxatricyclo[5.2.1.02,6]decan-3-yl methacrylate

HRID 1672109

Reaction equation

C(O[CH:5]1[O:13][CH2:12][CH:11]2[C:6]1([CH3:15])[CH:7]1[CH2:14][CH:10]2[CH2:9][CH2:8]1)(=O)C.[C:16]([OH:21])(=[O:20])[C:17]([CH3:19])=[CH2:18]>C(C1C(O)=C(C(C)(C)C)C=C(C)C=1)C1C(O)=C(C(C)(C)C)C=C(C)C=1>[C:16]([O:21][CH:5]1[O:13][CH2:12][CH:11]2[C:6]1([CH3:15])[CH:7]1[CH2:14][CH:10]2[CH2:9][CH2:8]1)(=[O:20])[C:17]([CH3:19])=[CH2:18]

Participants

Conditions

Temperature: 50 °C

Procedure

A mixture of 73 g of 2-methyl-4-oxatricyclo[5.2.1.02,6]decan-3-yl acetate, 150 g of methacrylic acid, and 40 mg of 2,2′-methylenebis(6-t-butyl-p-cresol) was heated at 50° C. under atmospheric pressure for 30 minutes, after which under a reduced pressure of 0.20 kPa, the reaction mixture was heated for 18 hours for distilling off the acetic acid formed. The reaction mixture was purified by distillation, obtaining 72 g (yield 91%) of the target compound.

Workup

temperatureafter which under a reduced pressure of 0.20 kPa, the reaction mixture was heated for 18 hours
distillationfor distilling off the acetic acid
customformed
distillationThe reaction mixture was purified by distillation

Sources & evidence

ORD record: ord-dbb818ad76da41ec8fa0de0bf7537b7b
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07998657B2

Linked notes

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