N-(cyclopropylmethoxy)-5-(2-fluoro-4-iodophenylamino)imidazo[1,5-a]pyrazine-6-carboxamide → 5-(4-Bromo-2-fluorophenylamino)-N-(cyclopropyl-methoxy)imidazo[1,5-a]pyrazine-6-carboxamide
Reaction equation
[CH3:27][O:28][C:29]([c:30]1[n:31][cH:32][c:33]2[n:34]([cH:35][n:36][cH:37]2)[c:38]1[NH:39][c:40]1[cH:41][cH:42][c:43]([Br:44])[cH:45][c:46]1[F:47])=[O:48].[CH:1]1([CH2:4][O:5][NH:6][C:7](=[O:8])[c:9]2[n:10][cH:11][c:12]3[n:13]([c:14]2[NH:15][c:16]2[c:17]([F:23])[cH:18][c:19]([I:22])[cH:20][cH:21]2)[cH:24][n:25][cH:26]3)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][O:5][NH:6][C:7](=[O:8])[c:9]2[n:10][cH:11][c:12]3[n:13]([c:14]2[NH:15][c:16]2[c:17]([F:23])[cH:18][c:19]([Br:44])[cH:20][cH:21]2)[cH:24][n:25][cH:26]3)[CH2:2][CH2:3]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f8c9c53cdfb84d6ba2cf961e8971128f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)