Benzene → 3,4-dihydro-6-(1,1-dimethylethyl)-8-iodospiro-[2H-1,3-benzoxazine-2,4'-tetrahydrothiopyran]

HRID 167437

Reaction equation

HRID 167437 reaction equation
[NH2:1][CH2:2][c:3]1[c:4]([OH:14])[c:5]([I:13])[cH:6][c:7]([C:9]([CH3:10])([CH3:11])[CH3:12])[cH:8]1.[S:15]1[CH2:16][CH2:17][C:18](=[O:21])[CH2:19][CH2:20]1.[cH:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1>>[NH:1]1[CH2:2][c:3]2[c:4]([c:5]([I:13])[cH:6][c:7]([C:9]([CH3:10])([CH3:11])[CH3:12])[cH:8]2)[O:14][C:18]12[CH2:17][CH2:16][S:15][CH2:20][CH2:19]2

Participants

4

Reactant 3

HCID 241BenzeneHCID 66173Tetrahydrothiopyran-4-oneHCID 1192862-Aminomethyl-4-t-butyl-6-iodophenol

Product 1

HCID 128578993,4-dihydro-6-(1,1-dimethylethyl)-8-iodospiro-[2H-1,3-benzoxazine-2,4'-tetrahydrothiopyran]

Sources & evidence

ORD record
ord-1cba6a048a9c4b68af7d51b002b3793f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

Loading…