4-Methylanisole → 2-Fluoro-2'-methoxy-5'-methylbiphenyl-4-yl 4-fluorophenyl sulfone

HRID 167674

Reaction equation

HRID 167674 reaction equation
[BH:19]([OH:20])[OH:21].[Br:1][c:2]1[c:3]([F:18])[cH:4][c:5]([S:8](=[O:9])(=[O:10])[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[cH:6][cH:7]1.[CH3:22][c:23]1[cH:24][cH:25][c:26]([O:29][CH3:30])[cH:27][cH:28]1>>[c:2]1(-[c:25]2[cH:24][c:23]([CH3:22])[cH:28][cH:27][c:26]2[O:29][CH3:30])[c:3]([F:18])[cH:4][c:5]([S:8](=[O:9])(=[O:10])[c:11]2[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 77314-MethylanisoleHCID 61668Boronic AcidHCID 684345101-Bromo-2-fluoro-4-[(4-fluorophenyl)sulfonyl]benzene

Product 1

HCID 684369542-Fluoro-2'-methoxy-5'-methylbiphenyl-4-yl 4-fluorophenyl sulfone

Sources & evidence

ORD record
ord-c05a311de66247de932e5e3f4d283d8e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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