2,6-Difluoro-4-iodobenzonitrile → 2,6-Difluoro-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-8-yl)benzonitrile

HRID 1677657

Reaction equation

HRID 1677657 reaction equation
[C:1]1(=O)[C:5]2=[CH:6][CH2:7][CH2:8][CH2:9][N:4]2[CH:3]=[N:2]1.[F:11][C:12]1[CH:19]=[C:18](I)[CH:17]=[C:16]([F:21])[C:13]=1[C:14]#[N:15]>>[F:11][C:12]1[CH:19]=[C:18]([CH:6]2[CH2:7][CH2:8][CH2:9][N:4]3[CH:3]=[N:2][CH:1]=[C:5]23)[CH:17]=[C:16]([F:21])[C:13]=1[C:14]#[N:15]

Participants

3

Reactant 2

HCID 190230682,6-Difluoro-4-iodobenzonitrileHCID 690431796,7-dihydro-5H-imidazo[1,5-a]pyridinone

Product 1

HCID 578143892,6-Difluoro-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-8-yl)benzonitrile

Procedure

starting from 6,7-dihydro-5H-imidazo[1,5-a]pyridinone [426219-51-4] and 2,6-difluoro-4-iodobenzonitrile [141743-50-2]

Sources & evidence

ORD record
ord-ada68d3797bd4ac4aba752c9c66899e5
Source dataset
uspto-grants-2011_08
Patent number
US08008334B2

Linked notes

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