Potassium 3-(N-acetylglycyl)dithiocarbazate → HCID 178474654, compound
Reaction equation
[C:1]([NH:4][CH2:5][C:6]([NH:8][NH:9][C:10]([S-:12])=[S:11])=O)(=[O:3])[CH3:2].[K+]>S(=O)(=O)(O)O>[C:1]([NH:4][CH2:5][C:6]1[S:11][C:10]([SH:12])=[N:9][N:8]=1)(=[O:3])[CH3:2]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
Potassium 3-(N-acetylglycyl)dithiocarbazate (102.3 g) was added bit by bit to concd. sulfuric acid (1 liter) at 0° to 5° C and the mixture was stirred for an hour at the same temperature. The reaction mixture was added dropwise on crushed ice (c.a. 10 kg) under stirring. Precipitating crystals were collected by filtration to give 5-acetamidomethyl-1,3,4-thiadiazole-2-thiol (54.5 g). m.p. 200° to 203° C.
Workup
- additionThe reaction mixture was added dropwise
- customPrecipitating crystals
- filtrationwere collected by filtration
Sources & evidence
- ORD record
- ord-62e95a5dc5ef4b44888b136dbb7dcb36
- Source dataset
- uspto-grants-1978_03
- Patent number
- US04077965
Reaction notes
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