Acetone → 5-Benzyloxy-2,2-dimethyl-1,3-dioxane

HRID 1679025

Reaction equation

HRID 1679025 reaction equation
[CH2:1]([O:8][CH:9]([CH2:12][OH:13])[CH2:10][OH:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:14][C:15]([CH3:17])=O>C1C=CC=CC=1>[CH2:1]([O:8][CH:9]1[CH2:10][O:11][C:15]([CH3:17])([CH3:14])[O:13][CH2:12]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 180AcetoneHCID 2035672-(Phenylmethoxy)-1,3-propanediol

Product 1

HCID 203648895-Benzyloxy-2,2-dimethyl-1,3-dioxane

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Using the procedure of Example 51, 2-benzyloxy-1,3-propanediol and acetone were reacted, using benzene as solvent, to give, after distillation using a short path column, 5-benzyloxy-2,2-dimethyl-1,3-dioxane. The nmr spectrum was consistent with the assigned structure.

Workup

  1. customwere reacted
  2. customto give
  3. distillationafter distillation

Sources & evidence

ORD record
ord-80f56de90df74adaade2cd08e85c9ee3
Source dataset
uspto-grants-1978_03
Patent number
US04077982

Linked notes

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