1,1-Dihydroxypropan-2-one → 2,4-Diamino-6-hydroxymethylpteridine

HRID 1679257

Reaction equation

HRID 1679257 reaction equation
Cl.[NH2:2][C:3]1[N:8]=[C:7]([NH2:9])[N:6]=[C:5]([NH2:10])[C:4]=1[NH2:11].[OH:12][CH:13](O)[C:14](=O)[CH3:15]>O>[NH2:9][C:7]1[N:8]=[C:3]([NH2:2])[C:4]2[C:5](=[N:10][CH:15]=[C:14]([CH2:13][OH:12])[N:11]=2)[N:6]=1

Participants

4

Reactant 2

HCID 131809821,1-Dihydroxypropan-2-oneHCID 204773462,4,5,6-Tetraaminopyrimidine hydrochloride

Product 1

HCID 703472,4-Diamino-6-hydroxymethylpteridine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

reacting tetraaminopyrimidinehydrochloride with dihydroxyacetone in the presence of air and water and at a pH in the range of 5.5±0.2 to give 2,4-diamino-6-hydroxymethylpteridine;

Sources & evidence

ORD record
ord-293edadf43f540759ccd99f350e77e42
Source dataset
uspto-grants-1978_03
Patent number
US04080325

Linked notes

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