4-(Methoxymethoxy)-2-nitroaniline → 4-(Methoxymethoxy)benzene-1,2-diamine
Reaction equation
[N+:1]([C:4]1[CH:10]=[C:9]([O:11][CH2:12][O:13][CH3:14])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-])=O.[H][H]>[Pd].CO>[NH2:6][C:5]1[CH:7]=[CH:8][C:9]([O:11][CH2:12][O:13][CH3:14])=[CH:10][C:4]=1[NH2:1]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
A mixture of 3.5 g. of 2-nitro-4-methoxymethoxyaniline, 1 g. of 5% palladium-on-charcoal catalyst and 120 ml. of methanol is hydrogenated at ambient conditions. After the uptake of hydrogen is complete, the mixture is filtered and 1,2-diamino-4-methoxymethoxybenzene is obtained by evaporation of the solvent.
Workup
- additionA mixture of 3.5 g
- filtrationthe mixture is filtered
Sources & evidence
- ORD record
- ord-87bf21385b7541b5a1e57de83adcbadb
- Source dataset
- uspto-grants-1978_03
- Patent number
- US04080461
Reaction notes
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