Acetic Anhydride → Dimethyl 3-acetamidopentanedioate

HRID 1680669Notes

Reaction equation

HRID 1680669 reaction equation
[CH3:1][O:2][C:3](=[O:12])[CH2:4][CH:5]([NH2:11])[CH2:6][C:7]([O:9][CH3:10])=[O:8].[C:13](OC(=O)C)(=[O:15])[CH3:14]>N1C=CC=CC=1>[CH3:10][O:9][C:7](=[O:8])[CH2:6][CH:5]([NH:11][C:13](=[O:15])[CH3:14])[CH2:4][C:3]([O:2][CH3:1])=[O:12]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 253304Dimethyl 3-aminopentanedioate

Product 1

HCID 53657276Dimethyl 3-acetamidopentanedioate

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

21.7 Parts of 3-aminoglutaric acid dimethyl ester is acetylated with 100 parts by volume acetic anhydride in 130 parts by volume pyridine to give N-acetyl-3-aminoglutaric acid dimethyl ester which has the following structural formula ##STR17##

Sources & evidence

ORD record
ord-3a20e2a804b74e4f8978c83a20ace3fc
Source dataset
uspto-grants-1981_06
Patent number
US04275192

Reaction notes

Loading…