1,1'-Thiocarbonyldiimidazole → HCID 20454059, compound

Reaction equation

[CH:1]([NH:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:12](N(CC2C=CC=CC=2)CC2C=CC=CC=2)=[S:13])=[CH:7][CH:6]=1)=[O:2].[C:29](NNC1C=CC(N)=CC=1)(=O)C.C(N1C=CN=C1)(N1C=CN=C1)=S>>[C:1]([NH:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]=[C:12]=[S:13])=[CH:7][CH:6]=1)(=[O:2])[CH3:29]

Participants

Reactant 3

HCID 802641,1'-Thiocarbonyldiimidazole

HCID 81068Acetic acid, 2-(4-aminophenyl)hydrazide

HCID 23454956HCID 23454956, compound

Product 1

HCID 20454059HCID 20454059, compound

Procedure

4-(2-Acetylhydrazino)phenyl isothiocyanate was prepared as described for NA-11 in Example 4 with 1-acetyl-2-(4-aminophenyl)hydrazine (1.23 g, 0.0075 mole) and 1,1'-thiocarbonyldiimidazole (1.35 g, 0.0075 mole). Yield 1.20 g (77 percent), m.p. 172°-174° C.

Sources & evidence

ORD record: ord-a5acd6a6acba45bf8b94e6f4a43edd0d
Source dataset: uspto-grants-1981_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04276364

Reaction notes

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