[CH3:1][O:2][C@@H:3]1[O:8][C@H:7]([CH2:9][OH:10])[C@H:6]([OH:11])[C@H:5]([OH:12])[C@H:4]1[OH:13].CC1C=C(C(C)(C)C)C(O)=C(C(C)(C)C)C=1.[OH-].[Na+].[C:32]([O:36][CH2:37]CO)(=[O:35])[CH:33]=[CH2:34]>OP(O)=O.O[Mo](O)(=O)=O>[CH:3]1([O:2][CH2:1][CH2:37][O:36][C:32](=[O:35])[CH:33]=[CH2:34])[O:8][C@H:7]([CH2:9][OH:10])[C@H:6]([OH:11])[C@H:5]([OH:12])[C@H:4]1[OH:13]
A 20.0 g quantity of methyl β-D-galactoside (product of Nacalai Co., Ltd., a guaranteed reagent)was suspended in 150 ml of 2-hydroxyethyl acrylate. To the suspension were added 1.0 g of butylhydroxytoluene and 1.0 g of phosphomolybdic acid, and the mixture was stirred well and gradually heated. After heating to a temperature of 60° to 70° C., the mixture was further stirred for about 2 hours while maintaining the same temperature, and was neutralized with 2N sodium hydroxide. The obtained reaction mixture was purified in the same manner as in Example 1. A fraction (Rf =0.2) of the reaction mixture was concentrated, giving 15.8 g of galactosyloxyethylacrylate (HEA-Gal) as an oily product (yield 55%).
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