1,2-Difluoro-4-[(4-fluorophenyl)sulfonyl]benzene → [3-{2-Fluoro-4-[(4-fluorophenyl)sulfonyl]phenoxy}-5-(trifluoromethyl)phenyl]acetic acid
Reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.F[C:17]1[CH:22]=[CH:21][C:20]([S:23]([C:26]2[CH:31]=[CH:30][C:29]([F:32])=[CH:28][CH:27]=2)(=[O:25])=[O:24])=[CH:19][C:18]=1[F:33]>>[F:33][C:18]1[CH:19]=[C:20]([S:23]([C:26]2[CH:31]=[CH:30][C:29]([F:32])=[CH:28][CH:27]=2)(=[O:24])=[O:25])[CH:21]=[CH:22][C:17]=1[O:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:7]=1Participants
3
Procedure
The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from step (i).
Sources & evidence
- ORD record
- ord-070f14ca65694d739d8b74cdd443a331
- Source dataset
- uspto-grants-2012_04