HCID 67277101, compound → 2-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid

HRID 1694744

Reaction equation

HRID 1694744 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]([CH3:14])[CH3:13])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1I.B([C:18]1[CH:29]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:27]=[CH:26][C:19]=1[O:20][C@@H:21]([CH3:25])[C:22]([OH:24])=[O:23])(O)O>>[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([N:12]([CH3:14])[CH3:13])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[C:26]1[CH:27]=[C:28]([C:30]([F:33])([F:32])[F:31])[CH:29]=[CH:18][C:19]=1[O:20][C@@H:21]([CH3:25])[C:22]([OH:24])=[O:23]

Participants

3

Reactant 2

HCID 67277101HCID 67277101, compoundHCID 672802043-Chloro-4-iodo-N,N-dimethylbenzenesulfonamide

Product 1

HCID 114764922-[[2'-Chloro-4'-[(dimethylamino)sulfonyl]-5-(trifluoromethyl)[1,1'-biphenyl]-2-yl]oxy]-(2S)-propanoic acid

Procedure

The title compound was prepared by the method of example 144 step (i) using the product from step (ii) and the product from example 146 step (iv).

Sources & evidence

ORD record
ord-9dd2adb4d5c140d6955b8e9b625e2da3
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Linked notes

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