(2S)-2-(2-borono-4-chlorophenoxy)-propanoic acid → HCID 58333648, compound

HRID 1694748

Reaction equation

HRID 1694748 reaction equation
B([C:4]1[CH:15]=[C:14]([Cl:16])[CH:13]=[CH:12][C:5]=1[O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9])(O)O.[Cl:17][C:18]1[CH:19]=[C:20]([S:25]([N:28]([CH3:30])[CH3:29])(=[O:27])=[O:26])[CH:21]=[CH:22][C:23]=1I>CO>[Cl:17][C:18]1[CH:19]=[C:20]([S:25]([N:28]([CH3:30])[CH3:29])(=[O:27])=[O:26])[CH:21]=[CH:22][C:23]=1[C:4]1[CH:15]=[C:14]([Cl:16])[CH:13]=[CH:12][C:5]=1[O:6][C@@H:7]([CH3:11])[C:8]([OH:10])=[O:9]

Participants

4

Reactant 2

HCID 67277298(2S)-2-(2-borono-4-chlorophenoxy)-propanoic acidHCID 67280204HCID 67280204, compound

Product 1

HCID 58333648HCID 58333648, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The title compound was prepared by the method of example 144 step (i) using the product from example 151 step (iv), the product from example 148 step (ii) and methanol as solvent. Yield (0.08 g).

Workup

  1. customYield (0.08 g)

Sources & evidence

ORD record
ord-58239a4d6a9a4aecbd462b5f965d84e1
Source dataset
uspto-grants-2012_04
Patent number
US08158820B2

Linked notes

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