HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromobenzonitrile → [(5-Chloro-3'-cyano[1,1'-biphenyl]-2-yl)oxy]-(2s)-propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromobenzonitrile | HCID 23381 | — |
| Reactant | (2S)-2-(2-borono-4-chlorophenoxy)-propanoic acid | HCID 67277298 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | [(5-Chloro-3'-cyano[1,1'-biphenyl]-2-yl)oxy]-(2s)-propanoic acid | HCID 11150790 | — |
Reaction Steps
The title compound was prepared by the method of example 144 step (i) using the product from example 151 step (iv), 3-bromobenzenenitrile and THF as solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08158820B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-5f53dcf244564fc2939ffd069027c9f7 |
| Source note | uspto-grants-2012_04 |